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Thanksgiving Turkey Meatloaf

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This Thanksgiving turkey meatloaf is the PERFECT non-traditional spin to the holiday meal! Super moist turkey meatloaf mixed with dried stuffing mix, fresh herbs, and topped with whole berry cranberry sauce – what’s not to love?

Thanksgiving turkey meatloaf sliced and staged with fresh herbs and extra cranberry sauce.

If there is anything that 2020 has taught us it’s that the holiday’s aren’t going to be normal either.

Honestly, it’s ok.

I’m not really on board with acting like everything is normal while also simultaneously ignoring science.

That’s not really my scene.

However, I am 100% on board with coming up new and fun different ways to celebrate the holidays.

That’s where this Thanksgiving turkey meatloaf comes into play.

It gives you all the flavors of Thanksgiving but rolled into one delicious turkey meatloaf.

Instead of ketchup topping I used whole berry cranberry sauce (with extra on the side for dipping!) and instead of using bread crumbs I used one bag of stuffing mix!

This meatloaf honestly might be my new favorite.

It’s that darn good!

Sliced Thanksgiving turkey meatloaf

What type of ground turkey should I use for meatloaf?

Now, I know there is a lot of hate on turkey meatloaf but honestly – I love it!

For this recipe I used 2 pounds of 93/7 ground turkey.

That means it has 7% fat in the meat.

The reason I like there to be some fat is so the baked meatloaf stays moist and does not dry out.

Could I used a different type of ground meat?


The reason I went with turkey is because it plays on the idea of a turkey dinner on Thanksgiving and naturally pairs well with the stuffing, cranberry sauce, and fresh herbs.

If you can’t easily find ground turkey you could use ground beef in place.

Just note, it will change the flavor profile if you opt to use ground beef.

What type of stuffing mix should I use?

I used one 6 ounce bag of UNCOOKED Stove Top stuffing mix in turkey flavor.

You could of course use chicken flavor stuffing mix too. They are both very similar.

The main reason I used a bag of Stove Top is because I knew it would be filled with flavors that traditionally taste like “Thanksgiving” and because the dried bread would be a great substitute for bread crumbs.

What if I want to use breadcrumbs in my meatloaf?

If you’re not a fan of Stove Top or just don’t want to buy a box of stuffing you can easily substitute a few things in its place.

You could substitute 6 ounces panko bread crumbs mixed with 1 teaspoon dried poultry seasoning.

Or if you have a bag of dried stuffing mix (the type sold in the bag with no other ingredients) use 6 ounces of that plus the addition of 1 teaspoon of dried poultry seasoning.

Thanksgiving turkey meatloaf sliced and plated

What type of cranberry sauce should I use?

You’ll want to make sure to glaze this Thanksgiving turkey meatloaf with a whole berry style of cranberry sauce.

So this means you can either buy it in a can (make sure it says whole berry!) or make it yourself!

I have a great Cranberry Orange Sauce with Ginger that would be perfect for this recipe!

How do I store this Thanksgiving turkey meatloaf?

Meatloaf is actually my all time FAVORITE breakfast leftover.

Yes, I eat dinner leftovers for breakfast.

I follow zero breakfast rules.

To store just sliced it, put it in an air-safe container, and store refrigerated for up to 4 days.

Sliced Thanksgiving turkey meatloaf surrounded by fresh herbs

Do you love this Thanksgiving turkey meatloaf?

Why not try a few of my other delicious Thanksgiving dishes!

thanksgiving turkey meatloaf sliced

Thanksgiving Turkey Meatloaf

Yield: 4-6 servings
Prep Time: 15 minutes
Cook Time: 45 minutes
Total Time: 1 hour

This Thanksgiving turkey meatloaf is the PERFECT non-traditional spin to the holiday meal! Super moist turkey meatloaf mixed with dried stuffing mix, fresh herbs, and topped with whole berry cranberry sauce - what's not to love?


  • 2 pounds ground turkey, 93/7
  • 1 (6 ounce) bag dried stuffing mix
  • 2 large eggs, cracked and whisked
  • 1/2 cup milk
  • 1 tablespoon Worcestershire sauce
  • 2 teaspoons minced fresh sage
  • 2 teaspoon minced fresh thyme
  • 2 teaspoons minced fresh rosemary
  • 1 (14 ounce) can whole berry cranberry sauce


  1. Preheat your oven to 375 degrees F and line a rimmed baking sheet with foil, parchment paper, or a Silpat liner.
  2. If you use foil spray the foil lightly with nonstick spray, set aside.
  3. In a large bowl add ground turkey, dried stuffing mix, eggs, milk, Worcestershire sauce, sage, thyme, and rosemary.
  4. Using your hands, or a spatula, gently mix together until well combined.
  5. Add the mixed meat to your prepared baking sheet and shape into a 12x8 inch loaf.
  6. Add to the preheated oven and bake for 30 minutes.
  7. Remove from the oven and top the meatloaf with about 1/2 the can of cranberry sauce.
  8. Place back in the oven and bake for another 15 minutes.
  9. Remove from the oven, test center to make sure the meatloaf has reached 165 degrees F, and serve sliced with extra cranberry sauce on the side.


  • I used Butterball 93/7 ground turkey
  • For the stuffing, I used 1 (6 ounce) bag of uncooked Stove Top turkey stuffing mix
Nutrition Information:
Yield: 6 Serving Size: 1
Amount Per Serving: Calories: 532Total Fat: 30gSaturated Fat: 8gTrans Fat: 1gUnsaturated Fat: 19gCholesterol: 224mgSodium: 257mgCarbohydrates: 23gFiber: 1gSugar: 15gProtein: 42g

This website provides approximate nutrition information for convenience and as a courtesy only. Nutrition information can vary for a variety of reasons. For the most precise nutritional data use your preferred nutrition calculator based on the actual ingredients you used in the recipe.

Did you make this recipe?

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Thanksgiving Turkey Meatloaf pin

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[…] Love all things turkey but don’t have the time? Try my Thanksgiving Turkey Meatloaf. […]

Lisa Joseph

Thursday 25th of November 2021

I made this for Thanksgiving and it was excellent! The only thing I changed was using Stove Top herb flavored stuffing mix and dried herbs. It is definately a keeper and I will be making this again

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Thursday 2nd of September 2021

[…] Thanksgiving Turkey Meatloaf […]

Joyce Matthews

Saturday 5th of December 2020

I found the Worcestershire sauce a bit overpowering. Other than that, the flavours were very good. I’ve made it twice, the second time, dividing the stuffing mix, with half going into the meat mixture (dry), the other half prepared with extra onion and celery (steam the chopped celery and use the cooking liquid to make the stuffing moist), and put into the middle layer of the meatloaf. The cooked slices are beautiful and festive.

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