Homemade Mississippi Pot Roast

4.67 from 3 votes
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This homemade Mississippi pot roast is made in the slow cooker and packs some big flavor. Serve over egg noodles, mashed potatoes, or even piled high on a bun. Plus this version is 100% homemade so it uses ingredients easily found in your pantry and no flavor packets!

Homemade Mississippi Roast shredded on a plate.
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There is nothing more I love than a big delicious pot roast. Even better when that roast is cooked up with a homemade ranch and pepperoncini!

This homemade Mississippi pot roast is the perfect balance of savory and zesty bite.

And while I love serving it over mashed potatoes I think my favorite way is hands down buttered noodles. It reminds me of classic beef and noodles but with a zip from the pepperoncini.

Plus if you’re into comfort meals this recipe is just that.

It’s perfect for cold winter nights or even summer since you won’t have to heat up your house to make it!

This version is made 100% from scratch with its own quick ranch dressing but read below if you’re short on time and want to make it the classic from flavor packets way.

Ingredients for Mississippi roast

  • Beef chuck roast – I like to use a boneless beef chuck roast for this recipe. This cut of roast is great for dishes for like this and shreds really easily.
  • Flour – After some seasonings you dredge the roast in flour and then brown it to lock in flavor. The flour helps brown it up nicely.
  • Pepperoncini – This adds a bite to the meat that is part zesty and part tangy.
  • Mayonnaise – The base for the homemade ranch dressing.
  • Apple cider vinegar – The tang needed for a creamy dressing.
  • Buttermilk – This helps bring fat to the dish and flavor to the dressing.
  • Dill and sweet paprika – Just some simple flavorings for the ranch that will get mixed with the roast.
Homemade Mississippi Roast on a white plate with peppers.

What is Mississippi Pot Roast

Mississippi pot roast is a simple roast recipe that is traditionally made with au jus mix, ranch seasoning, butter, and pepperoncini.

It’s savory and tangy and the perfect cold winter meal.

It was invented by Robin Chapman of Ripley, Mississippi in the 1990s. Don’t you just love how a simple recipe invented in the 90s can become a worldwide thing?

How to serve homemade Mississippi roast

My 3 favorite ways to serve this roast are by spooning it over mashed potatoes, buttered noodles, or on a soft pillowy bun.

For a fun twist serve it over my Instant Pot mashed sweet potatoes.

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Tips and tricks

This recipe is very simple but that doesn’t mean there aren’t a few tips and tricks we can use along the way to make things even easier!

  1. Make sure to cook the roast low and slow for optimal tenderness. The sweet spot is 6 hours on low but it can be cooked up to 8 hours.
  2. While not searing the roast makes it slightly faster to prep I think this step really locks in flavor and gives it a depth of flavor that can often be lost in the slow cooker.
  3. Don’t want to make your ranch dressing? Replace with 1 pack powdered ranch dressing and 1 pack powdered beef au jus.

What to serve with pot roast

While I could happily eat this Mississippi roast with just noodles or potatoes I realize the importance of vegetables. Here are a few recipes to serve alongside this dish:

Homemade Mississippi Roast shredded on a white plate.

More slow cooker recipes

4.67 from 3 votes

Homemade Mississippi Pot Roast

By: Brandy O’Neill – Nutmeg Nanny
Servings: 6 servings
Prep: 20 minutes
Cook: 8 hours
Total: 8 hours 20 minutes
This homemade Mississippi roast is made in the slow cooker and packs some big flavor. Serve over egg noodles, mashed potatoes or even piled high on a bun. Plus this version is 100% homemade so it uses ingredients easily found in your pantry and no flavor packets!
This homemade Mississippi pot roast is made in the slow cooker and packs some big flavor. Serve over egg noodles, mashed potatoes, or even piled high on a bun. Plus this version is 100% homemade so it uses ingredients easily found in your pantry and no flavor packets!
Want to save this recipe?
Enter your email below and we’ll send the recipe straight to your inbox!

Ingredients 

  • 1 4 pound boneless beef chuck roast
  • 2 teaspoons kosher salt
  • 2 teaspoons fresh cracked pepper
  • 1/4 cup all-purpose flour
  • 3 tablespoons vegetable oil
  • 4 tablespoons unsalted butter
  • 12 whole pepperoncini
  • 2 tablespoons mayonnaise
  • 2 teaspoons apple cider vinegar
  • 1 teaspoon buttermilk
  • 1/2 teaspoon dried dill
  • 1/4 teaspoon sweet paprika

Instructions 

  • Layout the chuck roast and season both sides with kosher salt and pepper.
  • Dredge the roast in the flour to coat the roast.
  • In a large skillet add vegetable oil and set over medium-high heat.
  • Let the oil get hot just until it's lightly smoking. Add in the roast and cook for a few minutes on each side until it's browned and have a slight crust on the outside.
  • Add browned roast to your slow cooker.
  • Top the roast with your butter and place the pepperoncini around the roast.
  • Add the lid and put your slow cooker on low.
  • While your roast is warming up make your homemade ranch dressing by whisking together mayonnaise, apple cider vinegar, buttermilk, dried dill, and sweet paprika.
  • When the dressing is smooth pour over the roast in the slow cooker, put the lid back over the top, and cook on low for 6-8 hours.
  • After it has roasted for 6-8 hours it should easily pull apart and shred. Shred the beef, put it back into the slow cooker, and toss in the juices. Serve overtop egg noodles (my personal favorite), mashed potatoes, or on a bun.

Video

Notes

Nutrition

Serving: 1gCalories: 245kcalCarbohydrates: 12gProtein: 6gFat: 20gSaturated Fat: 7gPolyunsaturated Fat: 13gCholesterol: 34mgSodium: 2175mgFiber: 2gSugar: 5g

Nutrition information is automatically calculated, so should only be used as an approximation.

Additional Info

Course: Slow Cooker
Cuisine: American
Tried this recipe?Mention @NutmegNanny or tag #nutmegnanny!
Homemade Mississippi Roast pin for pinterest.

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About Brandy

I am a food lover and recipe developer bringing you delicious recipes that taste great and are easy to make! My food is inspired by travels around the world and my love of flavorful food. A list of things that make me happy: cats, Coke Zero, houseplants, and travel.

4.67 from 3 votes (3 ratings without comment)

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20 Comments

  1. Wow, this roast looks incredible! I definitely need to add this roast, noodles and veggies to my dinner menu soon.

  2. Never heard of this craze, but now that I have seen this deliciousness I am all over it! Can’t wait to try this recipe!

  3. WHAT a dinner! This looks so good (and easy). Great for a Sunday and to save leftovers for later in the week!

  4. Roasts in the crock pot are on of my go to meals….we love piling the meat on a yummy roll and eating them as sandwiches!

  5. I was just reading that NYT story about the roast last week, and so now that you are BEGGING me to make it, I will! Yours looks amazing!

  6. Whoa, that is one AMAZING roast!! I haven’t tried the Mississippi roast yet, because all the recipes I saw used the packets… and I don’t like how salty they make things… so I’m DEFINITELY going to try this homemade version 🙂

  7. AMAZING, OMG and all the other capitals you can think of, Ranch Dressing marinade…seriously shaking my head, blown away, will it work as a marinade for a london broil?